Catabasis Pharmaceuticals and Parent Project Muscular Dystrophy to Host a Webinar on PolarisDMD: Phase 3 Clinical Trial of Edasalonexent (CAT-1004) in Duchenne Muscular Dystrophy
Dr. Donovan will discuss the Phase 3 PolarisDMD clinical trial studying edasalonexent in Duchenne muscular dystrophy (DMD), which is enrolling boys ages 4 to 7 (up to 8th birthday) regardless of mutation type who have not been on steroids for at least 6 months. Topics will include discussion of the PolarisDMD clinical trial, endpoints, inclusion and exclusion criteria, and information on edasalonexent, including previous clinical results that showed preserved muscle function in boys affected by Duchenne with edasalonexent treatment compared to the off-treatment period as well as significantly improved biomarkers.
The webinar can be accessed by visiting http://bit.ly/2Puskwr.
Edasalonexent (CAT-1004) is an investigational oral small molecule that is being developed as a potential new standard of care for all patients affected by DMD, regardless of their underlying mutation. Edasalonexent inhibits NF-kB, which is a key link between loss of dystrophin and disease progression. NF-kB has a fundamental role in skeletal and cardiac muscle disease in DMD. Catabasis is currently enrolling the single global Phase 3 PolarisDMD trial to evaluate the efficacy and safety of edasalonexent for registration purposes. In the clinic, we observed that edasalonexent preserved muscle function and substantially slowed disease progression compared to rates of change in a control period, and significantly improved biomarkers. Edasalonexent continues to be dosed in an open-label extension of the MoveDMD Phase 2 clinical trial. The
Investor and Media Contact
Catabasis Pharmaceuticals, Inc.
Andrea Matthews, 617-349-1971